Is arachidonic acid an endoschistosomicide?
نویسندگان
چکیده
منابع مشابه
The compound 20-HETE is an arachidonic acid (ARA)
This article is available online at http://www.jlr.org The compound 20-HETE is an arachidonic acid (ARA) metabolite generated through the cytochrome P450 (CYP) pathway ( 1 ). CYP4A11, CYP4F2, CYP4F3, CYP2U1, and CYP1A1 are known to metabolize ARA to 20-HETE ( 2, 3 ). In addition, 20-HETE plays a role in regulating cardiovascular hemostasis ( 4 ) as a vasoconstrictor and platelet activator ( 5, ...
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Mechanosensitive ion channels have been described in many types of cells. These channels are believed to transduce pressure signals into intracellular biochemical and physiological events. In this study, the patch-clamp technique was used to idendfy and characterize a mechanosensitive ion channel in rat atrial cells. In cell-attached patches, negative pressure in the pipette activated an ion ch...
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Bradykinin-induced relaxation of precontracted, porcine coronary artery (PCA) rings is mediated by distinctly different endothelium-derived relaxing factors depending on the contractile agent used. Thus when contracted with KC1, bradykinin-induced relaxation of PCA rings is mediated solely by nitric oxide (NO), whereas when contracted with the thromboxane mimetic U46619, a small component of th...
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Cells were isolated from the outer medulla of the rabbit kidney, primarily from the thick ascending limb of Henle's loop (mTALH). These mTALH cells are heavily invested with a cytochrome P450-Iinked monooxygenase that represents the third pathway by which arachidonic acid is metabolized. After cell separation, approximately 80% of the cells proved to be mTALH in origin, based on electron micros...
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Macrophages produce various arachidonic acid (AA) metabolites which may either enhance or suppress inflammatory processes. We investigated AA metabolite production by alveolar macrophages (AMs) from 11 patients with pulmonary sarcoidosis and 9 normal volunteers. We assessed the production of both cyclooxygenase products (prostaglandin (PG) E2, thromboxane B2 (TXB2), PGF2 alpha, and 6-keto-PGF1 ...
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ژورنال
عنوان ژورنال: Journal of Advanced Research
سال: 2018
ISSN: 2090-1232
DOI: 10.1016/j.jare.2018.01.005